6. BMD in Spanish Type 1 DM
Microvascular complications: retinopathy, microalb/nephr, hx and pe for neuropath
Bone markers: Ca. Phos, TRAP, , PTH, OC
Microvascular complications: retinopathy, microalb/nephr, hx and pe for neuropath
Bone markers: Ca. Phos, TRAP, , PTH, OC
10. Bone Mineral Density in Patients with Type1 and Type 2 DM
(c-peptide stim)
Type 1 and Type 2 women used less estrogen
(c-peptide stim)
Type 1 and Type 2 women used less estrogen
11. Results
Reflects the mean age and BMI-adjusted BMD comparing T1 vs T2 and each type to control
-lower BMD in T1 vs. controls
-lower BMD in T1 vs. T2
-no significant difference in T2 vs. control
Reflects the mean age and BMI-adjusted BMD comparing T1 vs T2 and each type to control
-lower BMD in T1 vs. controls
-lower BMD in T1 vs. T2
-no significant difference in T2 vs. control
12. European Vertebral Osteoporosis Study- EVOS
Have you ever been told by a doctor that you have diabetes? If so, do you inject insulin?
Only non-insulin treated diabetics were included in comparison
Have you ever been told by a doctor that you have diabetes? If so, do you inject insulin?
Only non-insulin treated diabetics were included in comparison
14. Diabetes and Hip Fracture: Nord-Trondelag Health Survey
? Raises the question..is fracture related to BMD or risk of falling
? Raises the question..is fracture related to BMD or risk of falling
16. Type 2 DM and Fracture: Study of Osteoporotic Fractures
No increase seen with forearm fracturessthis was seen in other studies (Rotterdam)
No increase seen with forearm fracturessthis was seen in other studies (Rotterdam)
19. IGF-1
Lower good bp 3 and higher bad bp 1 and 4
Conclusion: Type 1 diabetics showed a lower bone mass, lower IGF-1, and alterations in IGFBP compared with Type 2 diabetics.
Lower good bp 3 and higher bad bp 1 and 4
Conclusion: Type 1 diabetics showed a lower bone mass, lower IGF-1, and alterations in IGFBP compared with Type 2 diabetics.
21. Calcium Metabolism
Diabetics with persistent MA had significantly lower 25OHD, 1,25OH D and OC than controls and subjects with normoalbuminuria
Diabetics with persistent MA had significantly lower 25OHD, 1,25OH D and OC than controls and subjects with normoalbuminuria